Muscarinic Acetylcholine Receptors

Muscarinic Acetylcholine Receptors (mAChRs) are important proteins located in cells throughout the body. They are responsible for mediating the effects of acetylcholine, a neurotransmitter. mAChRs play a critical role in many physiological processes, including muscle contraction, heart rate and rhythm, breathing, memory formation, salivation, sweating and digestion. Their dysregulation has been linked to a variety of diseases, such as Alzheimer's and Parkinson's. As such, they are an important target for many therapies, including those designed to treat neurological and gastrointestinal disorders.