Limb Buds

Limb buds are small, flat collections of cells that emerge during embryonic development as the precursors to the arms and legs of human and other animals. These buds develop into the limbs and the tissue surrounding them is the precursor for the muscles, connective tissue and nerve structures. The development of limb buds at specific stages of embryonic development is critical for the successful development of the appendages and deviations from the normal timetable of development can cause severe limb deformities. In addition, limb buds are crucial for scientific research since they allow us to better understand the processes of embryonic development.