Research Topic · Peer-Reviewed

Intracranial

Intracranial refers to the space within the cranial cavity enclosed by the skull, containing the brain, cerebrospinal fluid, and cerebral vasculature. Intracranial pressure (ICP) is the pressure exerted within this fixed compartment, governed by the Monro-Kellie doctrine, which holds that the combined volume of brai…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 111× across the literature 🗓 Reviewed July 2026

Overview

Intracranial refers to the space within the cranial cavity enclosed by the skull, containing the brain, cerebrospinal fluid, and cerebral vasculature. Intracranial pressure (ICP) is the pressure exerted within this fixed compartment, governed by the Monro-Kellie doctrine, which holds that the combined volume of brain tissue, blood, and cerebrospinal fluid is nearly constant, so that an increase in one component must be offset by a decrease in another. When compensatory mechanisms are exhausted—by hemorrhage, mass lesion, edema, or obstructed cerebrospinal fluid flow—ICP rises, reducing cerebral perfusion and risking herniation and ischemic injury. Intracranial pathology spans spontaneous and traumatic hemorrhage, primary and metastatic tumors such as meningioma and glioblastoma, infections including invasive aspergillosis, vascular lesions, and the sequelae of traumatic brain injury; sinonasal and skull-base disease can extend intracranially. Diagnosis relies on neuroimaging and clinical assessment, and management targets the underlying cause and control of pressure. Research relevant to this area examines outcomes after craniotomy for spontaneous intracranial hemorrhage, surgical management of intracranial aspergillosis, intracranial tumors with cranial-nerve syndromes, traumatic brain injury outcomes and predictors, radiosurgical target definition for meningioma, and meningioma pathogenesis. This peer-reviewed literature reflects the anatomy, pressure dynamics, and pathology of the intracranial compartment relevant to skull-base and sinonasal disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 111 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Intracranial, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Sinusitis.

This page summarises published research for orientation; it is not medical or professional advice.