Tuberculosis Drug Discovery

Tuberculosis (TB) is a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. Drug discovery for TB is an important step in combating the spread of the disease. The process includes the identification of compounds that can specifically target the bacteria responsible for the disease, allowing for effective and safe treatments. New compounds are discovered through chemical screening of existing compounds, natural products, and compounds from synthetic sources. The compounds that show promise as potential drug candidates are then tested for safety and effectiveness in the laboratory and then in clinical trials before use in the treatment of TB. This process is essential for the development of safe and effective drugs to reduce the prevalence of TB and improve the health of affected populations around the world.

← Journal of Respiratory Diseases

Related Articles

41 article(s) found
Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients
Full-text HTML Download PDF Download XML
Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients
Full-text HTML Download PDF Download XML
Evaluation of SterculiaUrens Gum as Novel Carrier for Oral Colon Targeted Drug Delivery System
Full-text HTML Download PDF Download XML
Discovery and Quantification in Mass Spectrometry-Based Proteomics
Full-text HTML Download PDF Download XML
Development of Poly-ε-Caprolactone Based Nanoadjuvant for Effective Vaccination Against Tuberculosis
Full-text HTML Download PDF Download XML
Current Status of Nonsteroidal Anti-Inflammatory Drugs in Colorectal Cancer Prevention
Full-text HTML Download PDF Download XML
Pseudotumor Tuberculosis Of Liver: A Rare Entity
Full-text HTML Download PDF Download XML
Synthesis and Assessment of a New Tetrahydrogeraniol Derivative as Penetration Enhancer for Transdermal Drug Delivery
Full-text HTML Download PDF Download XML
A Successful Vancomycin Treatment of Multidrug-Resistant MRSA-Associated Canine Pyoderma
Full-text HTML Download PDF Download XML
Trends and inducing factors for illicit drug use in Grenada: Epoch 2001 – 2009.
Full-text HTML Download PDF Download XML
Performance Assessment of Some Operational Aspects of Revised National Tuberculosis Control Programme in Tuberculosis Unit, Nagpur, India
Full-text HTML Download PDF Download XML
Synthesis of Labeled Rifabutin Dithiocarbamate: A Potential Mycobacterium Tuberculosis Imaging Agent
Full-text HTML Download PDF Download XML
Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug
Full-text HTML Download PDF Download XML
Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy
Full-text HTML Download PDF Download XML
Hepatic Tuberculosis of Pseudotumor Form
Full-text HTML Download PDF Download XML
Profile of Similarity of Electron Withdrawing Structure Towards Analgesic-Anti-Inflammatory Activity of The Novel Isatin Analogue: Design and Implementation of Phase I Drug Discovery
Full-text HTML Download PDF Download XML
Sulfonamides: Historical Discovery Development (Structure-Activity Relationship Notes)
Full-text HTML Download PDF Download XML
Evaluation of Bacterial Population in the Saliva of Drug Addicts
Full-text HTML Download PDF Download XML
Drug Design Progress of In silico, In vitro and In vivo Researches
Full-text HTML Download PDF Download XML
Drug Abuse among Street Children
Full-text HTML Download PDF Download XML
Effect of Coinfection by Fasciola hepatica and Mycobacterium bovis on Bovine Tuberculosis Immunodiagnosis in an Enzootic Area Hidalgo State, Mexico.
Full-text HTML Download PDF Download XML
The Pineal Hypothesis for Drug Dependence
Full-text HTML Download PDF Download XML
Why New Drugs, Treatments, and Medical Devices Still Needs to be Tested Clinically Before Making it Available in the Market?
Full-text HTML Download PDF Download XML
Successful Cascade of Care and Cure HCV in 5382 Drugs Users: How Increase HCV Treatment by Outreach Care, Since Screening to Treatment
Full-text HTML Download PDF Download XML
Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.
Full-text HTML Download PDF Download XML
Acute Peritonitis: A Rare Complication Revealing Intestinal Tuberculosis
Full-text HTML Download PDF Download XML
Factors Influencing Tuberculosis Knowledge among TB Patients in Gakenke District, Rwanda
Full-text HTML Download PDF Download XML
Lipid Assemblies as Tools for Drug Delivery
Full-text HTML Download PDF Download XML
Assessment of Self Medication Practice and Drugs Storage Among South Sudanese Community in Addis Ababa, Ethiopia
Full-text HTML Download PDF Download XML
Duodenocolic Fistula: A Rare Complication of Gastrointestinal Tuberculosis
Full-text HTML Download PDF Download XML
A Review on Drug Design by the Application of Computer
Full-text HTML Download PDF Download XML
Risk Management: Emerging critical issues during the hospital administration of drug therapy
Full-text HTML Download PDF Download XML
CalliphoraRomantis: Discovery of A New Species in The Field of Forensic Entomology
Full-text HTML Download PDF Download XML
A case of delayed allergy after cyanoacrylate closure of varicose veins, diagnosed by drug-induced lymphocyte stimulation test
Full-text HTML Download PDF Download XML
Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe
Full-text HTML Download PDF Download XML
Spirometric profile of people living with HIV on antiretroviral drugs in Abidjan
Full-text HTML Download PDF Download XML
The Application of Immunoglobulins Immune Response in the Discovery and Development of Safe Therapeutic Agents: A Review Article
Full-text HTML Download PDF Download XML
Measuring Quality Change in the Market for Anti-Ulcer Drugs
Full-text HTML Download PDF Download XML
Call to Action: The Need for Adverse Drug Event (ADE) Standardization and Codification Through Improved ADE Definitions, Documentation and Mapping, as well as More Refined Medication Definitions
Full-text HTML Download PDF Download XML
Toxicology and Drug Safety Issues: A Review Article
Full-text HTML Download PDF Download XML
Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy
Full-text HTML Download PDF Download XML