Tuberculosis Drug Discovery

Tuberculosis (TB) is a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. Drug discovery for TB is an important step in combating the spread of the disease. The process includes the identification of compounds that can specifically target the bacteria responsible for the disease, allowing for effective and safe treatments. New compounds are discovered through chemical screening of existing compounds, natural products, and compounds from synthetic sources. The compounds that show promise as potential drug candidates are then tested for safety and effectiveness in the laboratory and then in clinical trials before use in the treatment of TB. This process is essential for the development of safe and effective drugs to reduce the prevalence of TB and improve the health of affected populations around the world.

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Related Articles

41 article(s) found

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Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients

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Evaluation of SterculiaUrens Gum as Novel Carrier for Oral Colon Targeted Drug Delivery System

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Discovery and Quantification in Mass Spectrometry-Based Proteomics

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Development of Poly-ε-Caprolactone Based Nanoadjuvant for Effective Vaccination Against Tuberculosis

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Current Status of Nonsteroidal Anti-Inflammatory Drugs in Colorectal Cancer Prevention

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Pseudotumor Tuberculosis Of Liver: A Rare Entity

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Synthesis and Assessment of a New Tetrahydrogeraniol Derivative as Penetration Enhancer for Transdermal Drug Delivery

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A Successful Vancomycin Treatment of Multidrug-Resistant MRSA-Associated Canine Pyoderma

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Trends and inducing factors for illicit drug use in Grenada: Epoch 2001 – 2009.

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Performance Assessment of Some Operational Aspects of Revised National Tuberculosis Control Programme in Tuberculosis Unit, Nagpur, India

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Synthesis of Labeled Rifabutin Dithiocarbamate: A Potential Mycobacterium Tuberculosis Imaging Agent

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Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug

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Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy

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Hepatic Tuberculosis of Pseudotumor Form

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Profile of Similarity of Electron Withdrawing Structure Towards Analgesic-Anti-Inflammatory Activity of The Novel Isatin Analogue: Design and Implementation of Phase I Drug Discovery

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Sulfonamides: Historical Discovery Development (Structure-Activity Relationship Notes)

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Evaluation of Bacterial Population in the Saliva of Drug Addicts

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Drug Design Progress of In silico, In vitro and In vivo Researches

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Drug Abuse among Street Children

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Effect of Coinfection by Fasciola hepatica and Mycobacterium bovis on Bovine Tuberculosis Immunodiagnosis in an Enzootic Area Hidalgo State, Mexico.

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The Pineal Hypothesis for Drug Dependence

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Why New Drugs, Treatments, and Medical Devices Still Needs to be Tested Clinically Before Making it Available in the Market?

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Successful Cascade of Care and Cure HCV in 5382 Drugs Users: How Increase HCV Treatment by Outreach Care, Since Screening to Treatment

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Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.

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Acute Peritonitis: A Rare Complication Revealing Intestinal Tuberculosis

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Factors Influencing Tuberculosis Knowledge among TB Patients in Gakenke District, Rwanda

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Lipid Assemblies as Tools for Drug Delivery

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Assessment of Self Medication Practice and Drugs Storage Among South Sudanese Community in Addis Ababa, Ethiopia

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Duodenocolic Fistula: A Rare Complication of Gastrointestinal Tuberculosis

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A Review on Drug Design by the Application of Computer

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Risk Management: Emerging critical issues during the hospital administration of drug therapy

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CalliphoraRomantis: Discovery of A New Species in The Field of Forensic Entomology

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A case of delayed allergy after cyanoacrylate closure of varicose veins, diagnosed by drug-induced lymphocyte stimulation test

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Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe

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Spirometric profile of people living with HIV on antiretroviral drugs in Abidjan

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The Application of Immunoglobulins Immune Response in the Discovery and Development of Safe Therapeutic Agents: A Review Article

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Measuring Quality Change in the Market for Anti-Ulcer Drugs

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Call to Action: The Need for Adverse Drug Event (ADE) Standardization and Codification Through Improved ADE Definitions, Documentation and Mapping, as well as More Refined Medication Definitions

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Toxicology and Drug Safety Issues: A Review Article

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Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy

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