Peptide Nucleic Acid

(PNA) Peptide Nucleic Acid (PNA) is an artificially-synthesized molecule that can bind specifically to DNA and RNA sequences, having advantages over naturally-occurring nucleic acids. PNAs have a higher resistance to enzymes, improved binding affinity, and more stability than DNA, which makes them particularly useful in diagnostic and therapeutic applications. As a result, PNAs are commonly used in gene regulation, drug delivery, and in vitro diagnostics. PNA is also being developed for in vivo applications, including gene therapy, so that diseases may be treated by replacing defective genes with functional ones. Due to its wide range of potential applications, PNA is an exciting area of research that is paving the way forward for novel medical treatments.

← Journal of Peptides

Related Articles

35 article(s) found

Heart-Type Fatty Acid-Binding Protein Enables Rapid Risk Stratification in Patients with Pulmonary Embolism

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Physicochemical and Fatty Acids Composition of Barberry Integerrima Seed

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Metabolic Acidosis and Cardiovascular Disease in Patients on Peritoneal Dialysis

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Lactic Acidosis : A Poorly Understood Concept

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Template Independent Synthesis of Nucleic Acid Libraries

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The Antidepressant-Like Activity of the New Tetrapeptide Neuroprotector Kk-1, Homologous of Acth15-18 Sequence (An Experimental Study)

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Implementing High Energy Liquid Nutrition, Omega-3 Fatty Acids and Nutritional Supplements for the Treatment of Anorexia Nervosa

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Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug

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Docosahexaenoic Acid Supplementation is Not Anti- Inflammatory in Adipose Tissue of Healthy Obese Postmenopausal Women

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Research Progress of the Functional Nucleic Acid Techniques in GMO Detection

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Hydrolysis of Cellulose by Soluble Clostridium Thermocellum and Acidothermus Cellulolyticus Cellulases

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Consciousness Energy Healing Treatment: Impact on the Physicochemical and Thermal Characteristics of Folic Acid

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Preoperative and Postoperative N-terminal Pro B-type Natriuretic Peptide Levels Predict Cardiac Morbidity and Mortality in Patients Undergoing Colorectal Cancer Resection

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In Silico Inhibition of Essential Candida albicans Proteins by Arenicin, a Marine Antifungal Peptide

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‘A perfect Example of the Strong Ion Difference: Hyperchloraemic Acidosis due to 0.9% Normal Saline Irrigation, in a Patient with a Ruptured Bladder’

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Amino Acids and their Derivatives in Pathogenesis and Treatment of Liver Diseases

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RETRACTED: Amino Acid Imbalance in Atherosclerosis

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Formulation of Isohydricity Conditions in Acid-Base systems - A Review

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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

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Assessment of Traffic Policemen Exposure To Benzene by Using Trans, Trans-Muconic Acid Biomarker in Ahvaz City, Iran

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Effect of Trigonella Foenum against Ethylene Diamine Tetra Acetic Acid induced Nephrotoxicity in Male Albino Rats

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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

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Evaluation of Anti-oxidation and Therapeutic Effect of Biofield Energy Healing Based Novel Test Formulation Using TNBS (Tri Nitro Benzene Sulfonic Acid) - Induced Ulcerative Colitis in Sprague Dawley Rats

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Study of the Consciousness Energy Healing Treatment and It’s Effect on the Isotopic Abundance Ratio of Ascorbic Acid (Vitamin C)

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Ameliorative Potential of Chlorogenic Acid on Rotenone-Induced Neurotoxicity in Drosophila Melanogaster Model

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Iodometric Determination of Neutral Amino Acids Using Potassium Iodate

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Clinical Use of Peptide-Based Formula (Peptamen Junior®, Nestle) in the Paediatric Population

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Dual Energy Computed Tomography and Effect on the Management of Uric Acid Renal Calculi

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Dogonyaro-Leaf-Extract as Inhibitor for Aluminum Corrosion in Acid

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Soluble Biobased Substances in soil or Salicylic Acid on leaves affect the foliar pH and soil biovariability of Grapes-as explained by the NIR Spectroscopy of Litterbags and Teabags

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Novel Methods for Inhibiting Amyloidogenesis in the Presence of Peptides to Block Hydrophobic Interactions

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Peptide Synthesis in Aqueous Solution With a Reusable Solid Phase

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Protection Side Chain of Lysine by Host-Affinity Molecules during Solid Phase Peptide Synthesis in Aqueous Phase

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Degradation assessment of Vinyl Ester Matrix Fiber Reinforced Plastics Exposed to Cyclic Hydrochloric Acid Concentrations using Gravimetric Analysis for Chemical Storage Tank use

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Retraction Note: Amino Acid Imbalance in Atherosclerosis

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