2019
Overview
Elephantiasis is a chronic condition characterized by severe swelling and thickening of the skin and underlying tissues, most commonly affecting the limbs and genitals, typically caused by parasitic filarial worms transmitted through mosquito bites. Research published in Parasite Research has examined the persistence of lymphatic filariasis in specific geographic regions, including investigations of Bancroftian filariasis in Upper Egypt's Sohag Governorate, where endemic transmission has continued despite global elimination efforts. These studies document ongoing disease presence in particular foci, contributing to understanding of where parasitic infections remain entrenched and require sustained public health intervention. The condition develops when filarial parasites, particularly Wuchereria bancrofti, obstruct lymphatic vessels over years of chronic infection, leading to progressive tissue enlargement and disfigurement that can cause significant disability and social stigma. Research addressing the geographic distribution and persistence of filariasis in endemic areas remains essential for guiding targeted control programs, monitoring elimination progress, and identifying populations still at risk. Understanding local transmission patterns helps public health authorities allocate resources for mass drug administration campaigns and vector control measures aimed at interrupting parasite transmission and preventing new cases of this debilitating neglected tropical disease.
Research published in this journal
1 peer-reviewed article, ranked by relevance. Each links to its DOI.