Research Topic · Peer-Reviewed

Retinal Ganglion Cells

Retinal ganglion cells (RGCs) are the neurons of the innermost layer of the retina whose long axons form the optic nerve and carry visual information from the eye to the brain. They integrate signals relayed from photoreceptors through bipolar and amacrine cells, encode features such as contrast, motion, and color, …

Curated from this journal's research 📚 4 peer-reviewed articles cited Cited 21× across the literature 🔖 ISSN 2470-0436 🗓 Reviewed June 2026

Overview

Retinal ganglion cells (RGCs) are the neurons of the innermost layer of the retina whose long axons form the optic nerve and carry visual information from the eye to the brain. They integrate signals relayed from photoreceptors through bipolar and amacrine cells, encode features such as contrast, motion, and color, and include specialized subtypes that also support non-image functions like the regulation of circadian rhythms and the pupillary light reflex. Because RGCs are central to vision, their injury or progressive loss is a defining feature of optic neuropathies, including glaucoma, and is a key endpoint in studies of retinal and optic nerve health. Research in Ophthalmic Science engages directly with this cell population, including measurement of macular ganglion cell layer thickness in patients using oral isotretinoin and assessment of whether transiently raised intraocular pressure affects retinal function or causes retinal ganglion cell loss in an animal model, alongside related work on optic nerve head drusen and visual loss. This page gathers peer-reviewed, open-access research relevant to retinal ganglion cells, their structure and function, and their role in visual transmission and ocular disease.

Research published in this journal

4 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 4 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Retinal Ganglion Cells, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Ophthalmic Science (ISSN 2470-0436).

Journal editorial board
Argyrios Tzamalis · GREECE Brian M. DeBroff · United States Emanuela Interlandi · Italy

This page summarises published research for orientation; it is not medical or professional advice.