Research Topic · Peer-Reviewed

Demyelinating Disorders

Demyelinating disorders are a group of diseases in which the myelin sheath, the protective fatty covering that surrounds nerve fibers in the brain, spinal cord, and peripheral nerves, is damaged or destroyed. Myelin enables nerve signals to travel rapidly and efficiently, so its loss disrupts communication within th…

Curated from this journal's research 📚 2 peer-reviewed articles cited Cited 30× across the literature 🔖 ISSN 2470-0436 🗓 Reviewed June 2026

Overview

Demyelinating disorders are a group of diseases in which the myelin sheath, the protective fatty covering that surrounds nerve fibers in the brain, spinal cord, and peripheral nerves, is damaged or destroyed. Myelin enables nerve signals to travel rapidly and efficiently, so its loss disrupts communication within the nervous system and can produce a wide range of neurological symptoms depending on which nerves are affected, including weakness, numbness, problems with coordination and balance, and visual disturbances. Multiple sclerosis is the best-known demyelinating disease, but the category also includes other conditions affecting the central or peripheral nervous system, some of which are autoimmune, infectious, inherited, or related to other causes. Myelin in the central nervous system is produced by specialized cells called oligodendrocytes, and understanding how these cells develop and function is important to understanding both normal myelination and the processes that go wrong in demyelinating disease; research published through OpenAccessPub journals has examined oligodendrocyte development and the signaling pathways involved. Because demyelination can affect the visual pathways and eye movements, it is of particular relevance to ophthalmic science. As a topic within Ophthalmic Science, demyelinating disorders reflect interest in the neurological basis of visual and ocular symptoms and the broader study of nervous-system disease.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Demyelinating Disorders, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Ophthalmic Science (ISSN 2470-0436).

Journal editorial board
Argyrios Tzamalis · GREECE Brian M. DeBroff · United States Emanuela Interlandi · Italy

This page summarises published research for orientation; it is not medical or professional advice.