Research Topic · Peer-Reviewed

Age-related Macular Degeneration

Age-related macular degeneration (AMD) is a progressive eye disease that affects the macula, which is the part of the retina responsible for central vision. It is the leading cause of vision loss in individuals over the age of 50, and it is estimated that at least 11 million individuals in the United States are affe…

Curated from this journal's research 📚 11 peer-reviewed articles cited Cited 69× across the literature 🔖 ISSN 2470-0436 🗓 Reviewed June 2026

Overview

Age-related macular degeneration (AMD) is a progressive eye disease that affects the macula, which is the part of the retina responsible for central vision. It is the leading cause of vision loss in individuals over the age of 50, and it is estimated that at least 11 million individuals in the United States are affected by this condition. There are two types of AMD: dry AMD and wet AMD. Dry AMD occurs when small deposits of proteins, called drusen, accumulate in the macula, causing it to thin and deteriorate over time. Wet AMD, on the other hand, occurs when abnormal blood vessels grow underneath the macula, leaking fluid and blood that damage the retinal cells and cause vision loss. Risk factors for AMD include age, family history, smoking, obesity, high blood pressure, and light eye color. Symptoms of AMD may include blurry or wavy central vision, blind spots, or difficulty recognizing faces. Treatment for AMD depends on the type and severity of the disease. There is currently no cure for dry AMD, but lifestyle changes such as quitting smoking, eating a healthy diet, and taking nutritional supplements may slow its progression. Injections of anti-VEGF drugs directly into the eye can help slow the progression of wet AMD and may even improve vision in some cases. Early detection and treatment of AMD is crucial for preserving vision. Therefore, individuals at risk of AMD should have regular eye exams to monitor the health of their eyes and detect any potential issues early on.

Research published in this journal

11 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 11 articles above have been cited 69 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Age-related Macular Degeneration, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Ophthalmic Science (ISSN 2470-0436).

Journal editorial board
Argyrios Tzamalis · GREECE Brian M. DeBroff · United States Emanuela Interlandi · Italy

This page summarises published research for orientation; it is not medical or professional advice.