Zinc Finger Nucleases

Zinc Finger Nucleases (ZFNs) are specialized enzymes used to modify DNA. ZFNs consist of two protein modules that act as scissors, making a double-stranded break in the DNA. This technology is used in a variety of gene-editing processes, allowing for targeted insertion, deletion, or modulation of gene expression. ZFNs are highly precise and can be used to target and modify specific genes, including those associated with genetic disorders, making them an important tool in applied biotechnologies. In addition, ZFNs have been used to generate animal models that are beneficial for research purposes, providing scientists new avenues to explore the molecular basis of disease.