Natural Antisense Transcripts

Natural antisense transcripts (NATs) are non-coding RNAs that form complementary base pairs with a protein-coding gene, regulating its expression. NATs play a vital role in gene regulation and development, and their dysregulation is associated with diseases such as cancer and diabetes. NATs can be studied at the transcriptional, post-transcriptional, and epigenetic levels, offering insight into how genes are regulated, and how dysregulation of NATs may lead to disease. NATs can also be exploited as therapeutic targets, providing potential treatments for the diseases associated with their dysregulation. As such, NATs are becoming increasingly important in the field of biomedical research.

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