Liquid Chromatography-tandem Mass Spectrometry

(LC-MS/MS) Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) is a powerful analytical technique used by scientists and researchers to identify and quantify small molecules in complex mixtures. It combines the separation power of liquid chromatography with the specificity and sensitivity of tandem mass spectrometry. This powerful technique can be used to detect and measure very low concentrations of compounds—even individual molecules—in samples and to accurately quantify the levels of all compounds in the mixture, allowing for a comprehensive understanding of the sample. LC-MS/MS is widely used in fields such as pharmaceuticals, toxicology, nutrition, environmental analysis, forensics, and biotechnology.