Supercritical fluid extraction (SFE) is a separation technique that uses a supercritical fluid as the solvent to extract chemical compounds from a solid or liquid matrix. A supercritical fluid is a substance held above its critical temperature and pressure, where it exhibits properties intermediate between those of …
Supercritical fluid extraction (SFE) is a separation technique that uses a supercritical fluid as the solvent to extract chemical compounds from a solid or liquid matrix. A supercritical fluid is a substance held above its critical temperature and pressure, where it exhibits properties intermediate between those of a gas and a liquid: it can diffuse through materials like a gas while dissolving substances like a liquid. Carbon dioxide is the most widely used supercritical solvent because it is non-toxic, non-flammable, inexpensive, and reaches its critical point under relatively mild conditions, and its solvent strength can be tuned by adjusting temperature and pressure. These features make SFE valuable for isolating sensitive compounds such as essential oils, flavours, fragrances, lipids, and bioactive plant constituents without leaving harmful solvent residues. After extraction, the fluid can simply be returned to gas-phase conditions, leaving a clean product and allowing the solvent to be recovered and reused. As a result, supercritical fluid extraction is regarded as an efficient and environmentally favourable method within analytical and industrial chemistry, with applications in food, pharmaceutical, and natural-product processing. This page gathers peer-reviewed, open-access research in New Developments in Chemistry relevant to extraction methods and the isolation of chemical compounds.
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 4 articles above have been cited 23 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.
A sample of recent works citing this journal's research on Supercritical Fluid Extraction, linking to each citing work.