Overview
Sodium channels are proteins embedded in cell membranes that allow sodium ions to pass into the cell, and they are essential to electrical signaling in excitable tissues such as nerve and muscle. Voltage-gated sodium channels open and close in response to changes in the membrane's electrical potential, and their rapid opening initiates and propagates the action potentials by which neurons and muscle cells communicate and contract. Because of this central role, sodium channels are a major focus of study in chemistry, physiology, and pharmacology, and they are the targets of numerous natural toxins and therapeutic drugs that block or modulate their activity. Research relevant to this topic includes work on naturally occurring toxins that act on sodium channels, such as studies of neosaxitoxin and gonyautoxins, paralytic shellfish toxins investigated for their effects in anesthesia and pain management, as well as related research on ion channel mutations affecting channel inactivation. As a topic in chemistry, sodium channels connect molecular structure, ion transport, and the action of channel-modulating compounds. This page gathers peer-reviewed, open-access research relevant to sodium channels and the broader field of chemical science.
Research published in this journal
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 4 articles above have been cited 13 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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Lissette Oyaneder et al. · 2025 · Toxicon
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2025 · Animals
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2025 · Toxicon
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Cristóbal Dörner et al. · 2025 · Animals
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Cristóbal A. Dörner et al. · 2023 · Austral journal of veterinary sciences
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2023 · The Journal of Knee Surgery
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2021 · The Journal of Knee Surgery
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A. Kuzmin et al. · 2020 · Limnology and Freshwater Biology
A sample of recent works citing this journal's research on Sodium Channels, linking to each citing work.