Research Topic · Peer-Reviewed

Salting Out

Salting out is a separation technique in which the addition of a high concentration of salt to an aqueous solution decreases the solubility of organic compounds or proteins, causing them to precipitate from solution. This phenomenon occurs because salt ions compete for water molecules, reducing the water available t…

Curated from this journal's research 📚 4 peer-reviewed articles cited Cited 23× across the literature 🔖 ISSN 2377-2549 🗓 Reviewed June 2026

Overview

Salting out is a separation technique in which the addition of a high concentration of salt to an aqueous solution decreases the solubility of organic compounds or proteins, causing them to precipitate from solution. This phenomenon occurs because salt ions compete for water molecules, reducing the water available to solvate the target compounds. Research published in New Developments in Chemistry has explored salting out within the broader context of extraction and analytical chemistry methods. Studies have examined liquid-liquid extraction techniques for isolating morphine and tramadol from biological samples, where salting out can enhance phase separation and improve recovery of target analytes. Additional work has investigated chemical sensors for metal detection in aqueous samples, where ionic strength and salting effects influence sensor performance and selectivity. The journal has also published research on the stability of biomolecules like insulin in complex media containing salts and chelating agents, where understanding salt-induced precipitation is critical for maintaining protein integrity. These investigations demonstrate the practical importance of salting out phenomena in analytical method development, pharmaceutical analysis, environmental monitoring, and biotechnology applications where precise control of solubility and separation efficiency is essential.

Research published in this journal

4 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 4 articles above have been cited 23 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Salting Out, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in New Developments in Chemistry (ISSN 2377-2549).

Journal editorial board
Annarita Del Gatto · Italy Bharat Gurale · United States Palani ELUMALAI · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.