Research Topic · Peer-Reviewed

S-nitrosylation

S-nitrosylation is a chemical process that occurs in biological systems and is being increasingly studied in the field of chemistry. It involves the addition of a nitric oxide group (NO) to a cysteine residue in a protein, resulting in the formation of an S-nitrosothiol group. Recent developments in chemistry have …

Curated from this journal's research 📚 1 peer-reviewed article cited Cited 3× across the literature 🔖 ISSN 2377-2549 🗓 Reviewed June 2026

Overview

S-nitrosylation is a chemical process that occurs in biological systems and is being increasingly studied in the field of chemistry. It involves the addition of a nitric oxide group (NO) to a cysteine residue in a protein, resulting in the formation of an S-nitrosothiol group. Recent developments in chemistry have revealed the significance of S-nitrosylation in regulating various biological processes such as protein-protein interactions, enzyme activity, and gene expression. Nitric oxide is a small molecule that plays a crucial role in cell signaling pathways and contributes to the regulation of many physiological processes. The addition of an NO group to cysteine residues can modify the activity of proteins and enzymes, leading to changes in cellular behavior. Researchers are exploring the potential therapeutic applications of S-nitrosylation, particularly in the treatment of cardiovascular diseases, cancer, and neurodegenerative disorders. By targeting specific cysteine residues in proteins that are involved in disease pathways, it may be possible to modulate cellular behavior and alleviate symptoms. Chemists are also developing new methods for detecting S-nitrosylation in biological systems. These techniques include modified mass spectrometry and fluorescent protein labeling, which enable researchers to visualize the distribution and activity of S-nitrosylated proteins in living cells. In conclusion, S-nitrosylation is an important and exciting development in the field of chemistry, with potential applications that may significantly impact human health. Continued research into this process is likely to uncover new insights into cellular signaling pathways and pave the way for the development of novel therapeutic approaches.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

How this research is being cited

The 1 article above has been cited 3 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.

A sample of recent works citing this journal's research on S-nitrosylation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in New Developments in Chemistry (ISSN 2377-2549).

Journal editorial board
Annarita Del Gatto · Italy Bharat Gurale · United States Palani ELUMALAI · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.