Purines are nitrogen-containing heterocyclic compounds that serve as fundamental building blocks of nucleic acids and play essential roles in cellular metabolism and energy transfer. Research published in New Developments in Chemistry addresses both the synthetic chemistry and biochemical characterization of purine-…
Purines are nitrogen-containing heterocyclic compounds that serve as fundamental building blocks of nucleic acids and play essential roles in cellular metabolism and energy transfer. Research published in New Developments in Chemistry addresses both the synthetic chemistry and biochemical characterization of purine-related compounds. Published work has explored the synthesis of modified purine nucleoside analogues, including cladribine and related derivatives, which are of interest for their potential therapeutic applications. The journal has also featured biochemical studies on xanthine oxidase, an enzyme critical to purine catabolism that catalyzes the oxidation of hypoxanthine and xanthine to uric acid in various organisms including sheep. Additionally, research has examined the relationship between isotopic composition and biological activity in polyphenolic compounds that interact with purine-dependent cellular processes. These investigations reflect the broader significance of purines in medicinal chemistry, enzymology, and metabolic biochemistry. Understanding purine synthesis, modification, and degradation pathways remains important for developing pharmaceutical agents and elucidating fundamental biochemical mechanisms across diverse biological systems.
3 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 3 articles above have been cited 5 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Purines, linking to each citing work.