Research Topic · Peer-Reviewed

Protein Expression

Protein expression is the cellular process by which the information encoded in a gene is used to synthesize a functional protein, encompassing transcription of DNA into messenger RNA and its translation by ribosomes, followed by folding and post-translational modification. The term also denotes the experimental prod…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 74× across the literature 🔖 ISSN 2377-2549

Overview

Protein expression is the cellular process by which the information encoded in a gene is used to synthesize a functional protein, encompassing transcription of DNA into messenger RNA and its translation by ribosomes, followed by folding and post-translational modification. The term also denotes the experimental production of a target protein in host systems—bacterial, yeast, insect, or mammalian cells—for structural, functional, and biochemical study or for biotechnological and therapeutic use. Expression levels are governed by transcriptional and translational regulation, mRNA stability, and signaling inputs, and can be quantified by techniques such as immunoblotting, quantitative PCR, and mass-spectrometry-based proteomics. Differential and inducible expression underlies cellular responses to mechanical, inflammatory, and pathological stimuli, and altered expression of specific proteins is implicated in cancer, fibrosis, and other disease. Recombinant and overexpression strategies allow proteins to be obtained in quantities sufficient for downstream analysis and engineering. The research reflected here includes substrate-stiffness regulation of connective tissue growth factor expression, comparative proteomic analysis of surfactant proteins in transgenic models, transcription-factor-mediated control of inflammatory signaling, characterization of RNA-binding proteins, and overexpression effects on tumor metastasis. The journal publishes peer-reviewed studies on protein expression, regulation, and proteomic characterization across biochemical and biomedical contexts.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 74 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.

A sample of recent works citing this journal's research on Protein Expression, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Journal of New Developments in Chemistry (ISSN 2377-2549).

Journal editorial board
Zhe-Sheng Chen · United States Abel Jose de Sousa Costa Vieira · Portugal Amirhassan Amiri · Iran, Islamic Republic of

This page summarises published research for orientation; it is not medical or professional advice.