Protein Expression

Protein expression is a vital process in biochemistry that involves the synthesis of proteins in living organisms. Proteins are essential molecules that control nearly every function of living cells. They are involved in many major biological processes, including metabolism, gene expression, cell signaling, and immune response. To study or manipulate these processes, scientists often need to express specific proteins in a controlled way. Recent developments in chemistry have allowed for new methods of protein expression, improving the efficiency and precision of the process. One such development is the use of synthetic biology techniques. Synthetic biology involves the design and construction of new biological systems with predefined functions. It is a multidisciplinary area that combines biology, chemistry, and engineering. Synthetic biology allows scientists to manipulate DNA sequences and control the expression of specific proteins. This technique has been used to create microbial factories for producing proteins, which can be used in therapeutic drugs or industrial processes. Another recent development in protein expression is the use of CRISPR-Cas9. CRISPR-Cas9 is a powerful gene editing tool that can cut and edit DNA sequences with high precision. Scientists are now using this technology to control protein expression by targeting and modifying certain DNA sequences that regulate the process. This approach allows scientists to precisely control the levels and timing of protein expression, which has important implications in various fields of research, including drug development and gene therapy. In summary, the recent developments in protein expression have been instrumental in advancing the understanding and manipulation of biological processes. These advances have enabled scientists to control protein expression with greater efficiency and precision, unlocking new possibilities for the development of therapeutic drugs, biotechnology, and synthetic biology. As chemistry continues to evolve, we can expect even more exciting developments in protein expression technologies.

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46 article(s) found

Eukaryotic Signature Proteins

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Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells

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Human Myxomatous Mitral Valves Exhibit Focal Expression of Cartilage-Related Proteins

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Heart-Type Fatty Acid-Binding Protein Enables Rapid Risk Stratification in Patients with Pulmonary Embolism

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Correlation of Cryptococcal Antigen Assay with C-reactive Protein as Serum and Urine Biomarker in Cryptococcal Meningitis: Experience in a Tertiary Hospital

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Daily Saliva and Vaginal Mucins Co-vary in Protein-to-Carbohydrate Ratio

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Proteome and Proteomics: from Single Protein to Whole Body

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Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer

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Mechanisms Associated with Acquisition of Resistance to Butyrate-Induced Apoptosis in Colorectal Cancer Cells Using Gene Expression Analysis

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Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression

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MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter

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Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia

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High expression of miR-21 in tissue correlated with the poor survival of patients with esophageal cancer: a pilot study using the meta-analysis

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A Pilot Study Assessing the Impact of a High Protein Supplementation Diet on Fat Mass in Obese Adolescents with and without Type 2 Diabetes

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Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis

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Expression of Estrogen Receptor β in Hypothalamic Stem Cells

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Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy

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Study of VCAM-1 Gene Expression in Normal and Tumoral Tissues in Patients with Colorectal Cancer

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Total Proteins, β- and γ-globulins as efficacy therapy response indicators in dogs infected with Leishmania infantum – a Review

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Blockade of Programmed Cell Death Protein-1 Pathway for the Treatment of Melanoma

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Identification and Expression Analysis of Fragaria Vesca MLO Genes Involved in Interaction with Powdery Mildew (Podosphaera Aphanis)

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Study of Neuropilin-1/Cd304 Expression in Leukemogenesis

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Bisphenol A Down-Regulates The mRNA Expression of Steroidogenic Genes and Induces Histopathological Changes in Testes Of Rats

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Metal Metalloproteinase 2 is Differentially Regulated by the Interplay between Glucose and Insulin

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In Silico Inhibition of Essential Candida albicans Proteins by Arenicin, a Marine Antifungal Peptide

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Adrenomedullin as a Protein with Multifunctional Behavior and Effects in Various Organs and Tissues

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Examination of Maternal Assets and Breast Milk Expression

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Research Status and Application Prospect of Epigenetic Regulation of BDNF Gene Expression in Chronic Pain 

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Alpha-Fetoprotein and its Receptor: More Than Oncofoetal Antigens.

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Effect of a High Fat and High Protein Diet on Exercise-Induced Skeletal Muscle Hypertrophy in Rats

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Auricularia Polytricha (Mushroom) Regulates Testicular DNA Expression and Oxidative Stress Markers of Streptozotocin-Induced Diabetic Male Wistar Rat

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Cloning, Expression and Characterization of the α-glucuronidase from the Hyperthermophile DictyoglomusturgidumDSM 6724Ô

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Survival Rate and Growth Performances on Pre-Grossing of the African Cyprinidae LabeobarbusBatesii (Boulenger, 1903) According to the Level of Dietary Protein

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Quercetin Attenuates Manganese-Induced Neurotoxicity in Mice Hippocampus by Regulation of Oxidative Stress and Tumour Necrosis factor Alpha Expression 

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Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis

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Evaluation of Vitamin D3 metabolite (25-OH Vit D3), Neurotransmitter (ACh), and the Expression of Proinflammatory Cytokines (IL-6 and TNF-α) in Tissue Homogenate after Administration of Biofield Energy Healing-based Novel Proprietary Test Formulation and Biofield Treatment per se to the Animals in Vitamin D3 Deficiency Diet (VDD)-induced Sprague Dawley Rats

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Cytokine Expression in Peripheral Blood Mononuclear Cell Cultures Obtained from Cattle with Different Stages of Natural Mycobacterium bovis Infection

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Expression of Concern: Potential Risks and Unknown Effects of mRNA Vaccines on Population Health (6th Rev). Damages Are Being Materialized

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Modeling of the Deposition of Low-Density Lipoprotein Particles inside an Ideal Geometry of the Heart Coronary Arteries

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Marginal SARS-CoV-2 Spike Protein Increases Interferon and Balances Cytokine Gene Expression

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Functional properties of Watermelon (Citrullus lanatus) and Pumpkin seed flours and protein isolate

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Effect of Protein and Energy-Dense Nutritional Supplement with Immunonutrients on Cachexia in Cancer Patients: An Open-Label, Single-Arm Study Among Indian Patients

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Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa

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Dynamic MicroRNA-Expression in Plasma of Melanoma Patients Correlates With Progression, PD-L1 Status and Overall Survival

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Newborns' MicroRNA Expression as Potential Biomarkers for Disease Diagnosis

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Understanding Inherited Bleeding Disorders: Genetic Mutations in Blood Coagulation Factors and Regulatory Proteins

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