Protein Complexes

Protein complexes are groups of two or more proteins that are joined together to perform specific biological functions. These complexes play a crucial role in many biological processes, such as enzyme catalysis, DNA replication and repair, gene expression, cell signaling, and many others. Recent developments in chemistry have allowed researchers to better understand the molecular structure and function of protein complexes. Advances in techniques such as X-ray crystallography, nuclear magnetic resonance imaging (NMR), and cryo-electron microscopy (Cryo-EM) have allowed scientists to visualize the architecture of these complexes at the atomic level. One of the most interesting areas of research in protein complex chemistry is the study of protein-protein interactions. Many protein complexes are formed through specific interactions between individual proteins. By understanding the nature of these interactions, researchers can manipulate and design new proteins that can be targeted to specific biological functions. Another exciting development in protein complex chemistry is the use of computational methods to model and predict protein-protein interactions. These methods rely on statistical analysis, molecular dynamics simulations, and machine learning algorithms to predict how individual proteins will interact and form complexes. As our understanding of protein complexes continues to grow, we are discovering new ways to use these complexes to develop new drugs, diagnostic tools, and other medical technologies. Ultimately, the study of protein complexes is helping us to understand the intricate workings of the molecular machinery that drives life, and paving the way for new breakthroughs in medical and biotechnological research.

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28 article(s) found
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Human Myxomatous Mitral Valves Exhibit Focal Expression of Cartilage-Related Proteins
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Heart-Type Fatty Acid-Binding Protein Enables Rapid Risk Stratification in Patients with Pulmonary Embolism
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Correlation of Cryptococcal Antigen Assay with C-reactive Protein as Serum and Urine Biomarker in Cryptococcal Meningitis: Experience in a Tertiary Hospital
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Daily Saliva and Vaginal Mucins Co-vary in Protein-to-Carbohydrate Ratio
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Proteome and Proteomics: from Single Protein to Whole Body
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Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer
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Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression
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Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia
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A Pilot Study Assessing the Impact of a High Protein Supplementation Diet on Fat Mass in Obese Adolescents with and without Type 2 Diabetes
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Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis
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Total Proteins, β- and γ-globulins as efficacy therapy response indicators in dogs infected with Leishmania infantum – a Review
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Blockade of Programmed Cell Death Protein-1 Pathway for the Treatment of Melanoma
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Metal Metalloproteinase 2 is Differentially Regulated by the Interplay between Glucose and Insulin
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Synthesis and Analysis of Copper Neem (Azadirechta Indica) Soap-Nitro and Ethoxy Benzothiazole Complexes for Anti-Bacterial Activity Related with Skin Diseases
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In Silico Inhibition of Essential Candida albicans Proteins by Arenicin, a Marine Antifungal Peptide
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Adrenomedullin as a Protein with Multifunctional Behavior and Effects in Various Organs and Tissues
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Alpha-Fetoprotein and its Receptor: More Than Oncofoetal Antigens.
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Effect of a High Fat and High Protein Diet on Exercise-Induced Skeletal Muscle Hypertrophy in Rats
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Survival Rate and Growth Performances on Pre-Grossing of the African Cyprinidae LabeobarbusBatesii (Boulenger, 1903) According to the Level of Dietary Protein
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Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis
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Modeling of the Deposition of Low-Density Lipoprotein Particles inside an Ideal Geometry of the Heart Coronary Arteries
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Marginal SARS-CoV-2 Spike Protein Increases Interferon and Balances Cytokine Gene Expression
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Functional properties of Watermelon (Citrullus lanatus) and Pumpkin seed flours and protein isolate
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Effect of Protein and Energy-Dense Nutritional Supplement with Immunonutrients on Cachexia in Cancer Patients: An Open-Label, Single-Arm Study Among Indian Patients
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Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa
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Understanding Inherited Bleeding Disorders: Genetic Mutations in Blood Coagulation Factors and Regulatory Proteins
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