Polymerases

Polymerases are enzymes that play an essential role in chemical processes and the field of chemistry. These enzymes can be found in the cell and catalyze the polymerization of different molecules. Polymerases have revolutionized the field of chemistry through DNA replication, sequencing, and modification. One of the most important and widely studied polymerases is DNA polymerase. This enzyme is responsible for the replication of DNA molecules, which is a fundamental process in biological systems. DNA polymerase catalyzes the addition of nucleotides to the growing DNA chain, allowing the replication of the genetic information contained in the DNA molecule. Another vital class of polymerases is RNA polymerases. RNA polymerases are responsible for the transcription of DNA into RNA molecules. This process is critical for the expression of genes in different organisms, and it plays a crucial role in gene regulation. Polymerases have also played a crucial role in the development of technologies such as the polymerase chain reaction (PCR) and next-generation sequencing. PCR is a widely used technique for the amplification of DNA molecules, and it is based on the activity of DNA polymerase. PCR has revolutionized molecular biology and has become a cornerstone of many laboratory techniques. Recent developments in the field of polymerases have led to the discovery of new enzymes with novel activities. For example, new classes of polymerases involved in the synthesis of natural products have been identified, which could lead to the development of new drugs and antibiotics. Moreover, novel polymerases with enhanced activities and specificities have been engineered using protein engineering approaches. In summary, polymerases are essential enzymes in the field of chemistry and have contributed significantly to the advancement of science and technology. Future developments in this area are likely to impact many fields, including medicine, biotechnology, and materials science.


From: Journal of New Developments in Chemistry

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Editor-in-chief: Zhe-Sheng Chen, Professor Department of Pharmaceutical Sciences College of Pharmacy and Allied Health Professions St. John’s University
Publication Type: Open Access Journal
Description: Chemistry is a branch of physical science that studies the composition, structure, properties and change of matter. Chemistry includes topics such as the properties of individual atoms, how atoms form chemical bonds to create chemical compounds, the interactions of substances through inter molecular forces that give matter its general properties.