Phosphorothioates

Phosphorothioates are an important class of compounds in contemporary chemistry. They are essentially sulfur analogs of phosphates- a type of compound found in numerous biological systems. Phosphorothioates have widespread applications such as in the development of aptamers, antisense oligonucleotides or as organophosphate pesticides. A significant medical application of phosphorothioates is assisting in gene regulation. With molecular biologists, the use of antisense oligonucleotides or aptamers have been found successful in identifying and disabling or enhancing unwanted gene processes. Another important application of phosphorothioates is as an organophosphate pesticide, which serves as an alternative to the traditional phosphates. Phosphorothioates prevent insect pests from consuming plants that have been treated with this chemical. Furthermore, these compounds have also found applications in the development of optoelectronic devices, and sensors. Researchers have been exploring the potential of phosphorothioates in a range of novel applications such as creating smart interfaces, nanostructural assays, among other breakthroughs. In summary, phosphorothioates hold great potential in a broad range of applications in research, development, and medical areas. With their increased importance and functionality, scientific researchers have invested their efforts in developing efficient and innovative methods of synthesizing them sustainably, environmentally friendly, and in larger quantities. These efforts promise to enhance the applications of Phosphorothioates further and opens new and exciting opportunities in the fields of materials sciences, biomedical research, and beyond.


From: Journal of New Developments in Chemistry

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Editor-in-chief: Zhe-Sheng Chen, Professor Department of Pharmaceutical Sciences College of Pharmacy and Allied Health Professions St. John’s University
Publication Type: Open Access Journal
Description: Chemistry is a branch of physical science that studies the composition, structure, properties and change of matter. Chemistry includes topics such as the properties of individual atoms, how atoms form chemical bonds to create chemical compounds, the interactions of substances through inter molecular forces that give matter its general properties.