Overview
Nucleic acids are biopolymers, principally deoxyribonucleic acid and ribonucleic acid, built from nucleotide monomers that store, transmit, and express genetic information. Each nucleotide comprises a nitrogenous base, a five-carbon sugar, and a phosphate group; alternating sugar and phosphate units form a directional backbone, while complementary base pairing, adenine with thymine or uracil and guanine with cytosine, links strands and encodes sequence. DNA characteristically adopts an antiparallel double helix that serves as the template for replication and transcription, whereas RNA is typically single-stranded and adopts varied folded structures supporting roles in translation, catalysis, and regulation. Beyond their natural functions, nucleic acids are exploited as engineered and analytical tools. Functional nucleic acids, including aptamers and nucleic acid enzymes, are selected to bind targets or catalyze reactions, and synthetic chemistry enables construction of diverse molecular libraries, while microfluidic platforms integrate amplification and detection for sensitive, miniaturized assays. Studies in this area examine functional nucleic acid techniques applied to detection of genetically modified organisms, template-independent synthesis of nucleic acid libraries, and microfluidic nucleic acid assays that employ microRNAs as biomarkers for colon cancer screening, alongside broader genomic techniques. Together these connect the fundamental structure and base-pairing chemistry of nucleic acids to their use in diagnostics, biosensing, and molecular engineering, where sequence-specific recognition provides both biological function and analytical specificity.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Template Independent Synthesis of Nucleic Acid Libraries
Correlating 13C Isotope in Oligomeric Proanthocyanidins with their Anticancer Properties
Drug Design Progress of In silico, In vitro and In vivo Researches
The Novel Coronavirus 2019 (COVID-19): A Narrative Review
The Current Immunoassays and Emerging Immunogenomic Approaches for Immunomonitoring Cancer and Infectious Diseases
Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine
Production of dried tomato powder with a high concentration of functional components and nutrients
Consciousness Energy Healing Treatment: Impact on the Physicochemical and Thermal Properties of Pyridoxine HCl
How this research is being cited
The 12 articles above have been cited 52 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.
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2025 · Applied Sciences
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2025 · Antioxidants
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2025 · Chemical Engineering Journal
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Janka Vašková et al. · 2025 · Antioxidants
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Tea Petković et al. · 2025 · Applied Sciences
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2024 · Asian Journal of Science Technology Engineering and Art
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2024 · Reviews in Cardiovascular Medicine
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V. Lankin et al. · 2024 · Reviews in cardiovascular medicine
A sample of recent works citing this journal's research on Nucleic Acids, linking to each citing work.