Nitriles

Nitriles, also known as cyanides, are a class of organic compounds containing a triple bond between a carbon atom and a nitrogen atom. The general formula for nitriles is R-C?N, where R represents an alkyl or aryl group. Nitriles have a wide range of applications, including as solvents, starting materials for the synthesis of drugs and agrochemicals, and as catalysts. Recently, there have been several exciting developments in the field of nitrile chemistry, including the discovery of new methods for their synthesis and the elucidation of their unique properties. One area of particular interest is the use of nitriles as building blocks for the synthesis of complex molecules. Nitriles can undergo a variety of reactions, including hydrolysis and reduction, to yield a diverse array of functional groups. This versatility has led to the development of several new synthetic methodologies, including the use of nitrile oxide cycloadditions and nitrile imine cycloadditions in the preparation of heterocyclic compounds. Another area of active research is the study of the biological activity of nitriles. Several nitrile-containing compounds have shown promise as anti-cancer agents, due to their ability to inhibit specific enzymes. In addition, nitriles have shown antimicrobial activity, making them potential candidates for use in the development of new antibiotics. Overall, the field of nitrile chemistry continues to be an area of active research, with new developments and applications emerging regularly. As scientists continue to study and explore the unique properties of nitriles, we can expect new and exciting discoveries in the years to come.


From: Journal of New Developments in Chemistry

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Editor-in-chief: Zhe-Sheng Chen, Professor Department of Pharmaceutical Sciences College of Pharmacy and Allied Health Professions St. John’s University
Publication Type: Open Access Journal
Description: Chemistry is a branch of physical science that studies the composition, structure, properties and change of matter. Chemistry includes topics such as the properties of individual atoms, how atoms form chemical bonds to create chemical compounds, the interactions of substances through inter molecular forces that give matter its general properties.