2017
Overview
A heterocycle is a cyclic chemical structure in which the ring contains atoms of at least two different elements, typically carbon together with one or more heteroatoms such as nitrogen, oxygen, or sulfur. Heterocyclic structures are among the most common frameworks in organic and medicinal chemistry, with examples including pyrrole, pyridine, furan, and imidazole. Heterocycle structures matter because they form the core scaffolds of a large proportion of pharmaceuticals, agrochemicals, and natural products, where the heteroatoms influence reactivity, polarity, and biological activity. Key aspects include ring aromaticity and stability, the position and number of heteroatoms, methods of synthesis, and how structural modifications alter pharmacological properties. Nitrogen-containing heterocycles such as pyrrole are especially important in drug design, often serving as building blocks for anti-inflammatory and analgesic agents. Related open-access research available through this journal describes the synthesis and evaluation of a novel pyrrole-derived carboxylic acid compound designed as a potential analgesic and anti-inflammatory drug, illustrating how the pyrrole heterocycle contributes to a molecule's structure and activity.
Research published in this journal
1 peer-reviewed article, ranked by relevance. Each links to its DOI.
How this research is being cited
The 1 article above has been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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D. Tzankova et al. · 2022 · Pharmaceutical Chemistry Journal
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2022 · Pharmaceutical Chemistry Journal
A sample of recent works citing this journal's research on Heterocycle Structures, linking to each citing work.