Anhydrides

Anhydrides are chemical compounds that are commonly used in organic chemistry. They are formed by the dehydration of carboxylic acids or by combining two different carboxylic acid molecules. The resulting compound is a dimeric molecule with the general formula (RCO)2O, where R represents an alkyl or aryl group. Anhydrides have a wide range of applications in various fields, including pharmaceuticals, plastics, and lubricants. They can also be used as important reagents in organic synthesis reactions. One notable example is the use of acetic anhydride in the synthesis of aspirin. Research has shown that anhydrides can also exhibit potent biological activity, making them attractive as leads for drug discovery. This is due to their ability to react with different biological molecules, such as proteins and enzymes, and modify their functions. Recently, there have been new developments in the synthesis and modification of anhydrides, which have enabled the production of more specialized compounds with unique properties. For example, the modification of cyclophosphamide anhydride has allowed for the development of highly potent anticancer agents. In conclusion, anhydrides have proven to be versatile and important compounds in chemistry and various industries. Their wide range of applications make them valuable tools in research and development, highlighting the ongoing need for further exploration and innovation in this field.


From: Journal of New Developments in Chemistry

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Editor-in-chief: Zhe-Sheng Chen, Professor Department of Pharmaceutical Sciences College of Pharmacy and Allied Health Professions St. John’s University
Publication Type: Open Access Journal
Description: Chemistry is a branch of physical science that studies the composition, structure, properties and change of matter. Chemistry includes topics such as the properties of individual atoms, how atoms form chemical bonds to create chemical compounds, the interactions of substances through inter molecular forces that give matter its general properties.