Voxel-based Morphometry

Voxel-based Morphometry (VBM) is a neuroimaging technique that is used in neurological research and therapy. It is a tool for the analysis of the human brain structure, which allows for the identification of structural differences in the brain between individuals, groups or populations. The VBM technique uses magnetic resonance imaging (MRI) to obtain high-resolution images of the living brain. This imaging technique captures highly detailed images of the brain's structure, which are then analyzed using computational algorithms. The resulting analysis identifies differences in the brain structure that can be linked to neurological disorders, disease or trauma. One of the most significant applications of VBM is the identification of changes in gray matter density in the brain. Gray matter is the portion of the brain that contains the cell bodies of neurons and is critical for conscious mental processes such as perception, movement, and memory. By detecting changes in gray matter structures, researchers can gain insight into the mechanisms of neurological disorders such as Alzheimer's disease, depression, and schizophrenia. Voxel-based Morphometry has also been used in brain therapy. By detecting differences in the brain's structure, clinicians can develop targeted treatment plans that aim to improve the functional capabilities of affected areas. This technique has found applications in various neurological disorders like Parkinson's disease, Multiple Sclerosis, and Epilepsy. Advancements in technology, including the increased power and accuracy of MRI scanners and computing algorithms, have enabled further refinements in VBM techniques, enhancing the precision of the analysis of the human brain's structural variations. In conclusion, Voxel-based Morphometry is a crucial neuroimaging technique for studying the structure of the brain and its changes due to neurological diseases, disorders or trauma. Its use in therapy allows clinicians to target and treat affected areas of the brain, leading to improved patient outcomes.

From: Neurobiology

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Editor-in-chief: Zheng Jiang, Department of Neuroscience, The Johns Hopkins University School of Medicine.
Publication Type: Open Access Journal
Description: The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood.