Transient Receptor Potential Channels

Transient Receptor Potential (TRP) channels are a diverse group of ion channels that play a crucial role in the neurological research and therapy of numerous diseases affecting the central and peripheral nervous system. These ion channels are responsible for mediating several important physiological processes and functions, including pain transmission, thermoregulation, and sensory perception. Recent research suggests that TRP channels could be a promising therapeutic target for several neurological diseases such as neuropathic pain, epilepsy, and neurodegenerative disorders including Alzheimer's, Parkinson's, and Huntington's. In neuropathic pain, TRP channels are believed to play a central role in the pathophysiology of chronic pain by facilitating the release of pain mediators such as Substance P and Calcitonin Gene-Related Protein (CGRP) from sensory neurons. Targeting these channels offers a promising approach for the development of new analgesics effective at preventing chronic pain while limiting the development of opioid dependence. Moreover, TRP channels are also involved in the modulation of the immune and inflammatory responses, presenting a potential therapeutic target for the management of autoimmune and inflammatory diseases such as asthma, rheumatoid arthritis, and inflammatory bowel diseases. In conclusion, TRP channels represent a promising field for neurological research and therapy, with immense potential for the development of novel therapeutic agents for the treatment of various neurological diseases.


From: Journal of Neurological Research And Therapy

Related Article For "Transient Receptor Potential Channels"

About (54) results

Article:

Psychosocial Characterization of HIV Clients with Potential to be Change Agents for HIV Prevention in Uganda

Journal:

Clinical Research In HIV AIDS And Prevention

Article:

Correlation of Oncotype DX Recurrence Score with the Expression of Insulin Receptor Substrate Proteins in Estrogen Receptor + Breast Cancer

Journal:

Cancer Genetics And Biomarkers

Article:

Transient Left Bundle Branch Block During the Recovery Period of a Stress Test

Journal:

Hypertension and Cardiology

Article:

The Potentials of Antioxidant Micronutrients in the Management of Metabolic Syndrome

Journal:

Antioxidant Activity

Article:

Age Variation in Bitter Taste Perception in Relation to the Tas2r38 Taste Receptor Phenotype

Journal:

International Journal of Nutrition

Article:

Anti-Oxidant Phytochemicals as Potential Treatments for Age-Related Macular Degeneration

Journal:

Antioxidant Activity

Article:

MicroRNAs: As A Novel Potential Tool for Diagnosis, Prognosis, and Therapeutic Agents in Hypertension.

Journal:

Hypertension and Cardiology

Article:

MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter

Journal:

Evolving Stem Cell Research

Article:

Taller Haustral Folds in the Proximal Colon: A Potential Factor Contributing to Interval Colorectal Cancer

Journal:

Colon And Rectal Cancer

Article:

Gene-Eden-VIR: A Potential Natural Treatment for Cervical Cancer

Journal:

Cervical Cancer

Article:

A Potential New Technique to Estimate the Origins of Focal Atrial Tachycardias from 12-Lead Electrocardiograms

Journal:

Hypertension and Cardiology

Article:

Hand Grip Strength as A Potential Nutritional Assessment Tool in Long-Term Care Homes

Journal:

Aging Research And Healthcare

Article:

Ageing-Demographic Time-Bomb or Social Construct: Outline of the Potential Horizons and Opportunities

Journal:

Aging Research And Healthcare

Article:

Analysis of Effects of Kale Powder Consumption among Subjects with Potential Metabolic Syndrome: A Prospective Single-Arm Clinical Study

Journal:

Hypertension and Cardiology

Article:

Methionine and Antioxidant Potential

Journal:

Antioxidant Activity

Article:

Calcium Transient Assays for Compound Screening with Human iPSC-derived Cardiomyocytes: Evaluating New Tools

Journal:

Evolving Stem Cell Research

Article:

Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis

Journal:

Proteomics and Genomics Research

Article:

Synthesis of Labeled Rifabutin Dithiocarbamate: A Potential Mycobacterium Tuberculosis Imaging Agent

Journal:

Glycomics And Metabolism

Article:

Transiently Raised IOP Equivalent to That Experienced During Ocular Surgery Causes Moderate Inflammation but does not Affect Retinal Function or Result in Retinal Ganglion Cell Loss in An Animal Model

Journal:

Ophthalmic Science

Article:

Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug

Journal:

International Journal of Pain Management

Article:

Expression of Estrogen Receptor β in Hypothalamic Stem Cells

Journal:

Evolving Stem Cell Research

Article:

Green Economy and Occupational Health and Safety: Potential Impacts and Preventive Policies

Journal:

International Journal of Occupational and Environmental Medicine

Article:

Capsaicin: A Potential Therapy Adjuvant for Intestinal Bowel Disease

Journal:

Digestive Disorders And Diagnosis

Article:

Breast Cancer, Chemokines, And Metastasis: A Search for Decoy Ligands of the CXCR4 Receptor

Journal:

Neoplasms

Article:

Antioxidative Potential of Consciousness Energy Healing Treatment on HepG2 Cells and DMEM after Oxidative Stress Induced by Hydrogen Peroxide

Journal:

Antioxidant Activity

Article:

In Vitro Assessment of Estrogenic Potential of Biofield Energy Treatment using Human Endometrial Adenocarcinoma Cell Line

Journal:

Women's Reproductive Health

Article:

Potential Impact of Aedes Albopictus (Skuse,1894), an Arbovirus and Nematode Vector, on Human Public Health

Journal:

Public Health International

Article:

Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco and/or Alcohol-Induced Head and Neck Cancer

Journal:

Cancer Genetics And Biomarkers

Article:

Molecular Composition of and Potential Health Benefits Offered by Natural East African Virgin Sunflower Oil Products: A 400 MHz 1H NMR Analysis Study

Journal:

International Journal of Nutrition

Article:

Biolarvicidal Potentials of the Methanolic-Leaf-Extracts of Selected Tropical Plant Species

Journal:

Experimental and Clinical Toxicology

Article:

Alpha-Fetoprotein and its Receptor: More Than Oncofoetal Antigens.

Journal:

Cancer Genetics And Biomarkers

Article:

Retracted: Nutrient Foramen of Fibula in Relation to Distal end, Potential Implications for Vascularised Bone Graft Surgery

Journal:

International Journal of Human Anatomy

Article:

Domestic Pigeons As A Potential Hazzard For Transmission Of Some Human Protozoan Parasites

Journal:

Parasite Research

Article:

Association of BsmI and ApaI Polymorphisms of the Vitamin D Receptor Gene with Dyslipidemia in Patients with Coronary Artery Disease.

Journal:

Bioinformatics And Diabetes

Article:

A Study on Redox Potential of Phytochemicals and their Impact on DNA

Journal:

DNA And RNA Research

Article:

Assessment of Ocimum basilicum as Potentially Fruit Flies Attractant

Journal:

Agronomy Research

Article:

Caffeine Components Empower the Brain Potentiality

Journal:

Spine and Neuroscience

Article:

Investigation of Emerging Risk Factors and Isolation of Potential Pathogenic Bacteria from Domestic Dog Stool in Port Harcourt Metropolis, Niger Delta

Journal:

Zoological Research

Article:

Potential Impact of COVID-19 Outbreak on Education, Staff Development and Training in Africa

Journal:

International Journal of Coronaviruses

Article:

Therapeutic Potential of Autologous Adipose Derived Mesenchymal Stem Cells in Human POI and Ovarian Aging

Journal:

Evolving Stem Cell Research

Article:

Evaluation of Renal and Cardioprotective Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats

Journal:

Nephrology Advances

Article:

Evaluation of Antioxidative Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats

Journal:

Antioxidant Activity

Article:

Evaluation of Antioxidative Potential of the Biofield Energy Treated Proprietary Test Formulation on L-NAME and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats

Journal:

Antioxidant Activity

Article:

Effect of pH on Phytochemical and Antioxidant Potential of Satawar Tubers (Asparagus Racemosus Willd.)

Journal:

Antioxidant Activity

Article:

Ameliorative Potential of Chlorogenic Acid on Rotenone-Induced Neurotoxicity in Drosophila Melanogaster Model

Journal:

Public Health International

Article:

Expression of Concern: Potential Risks and Unknown Effects of mRNA Vaccines on Population Health (6th Rev). Damages Are Being Materialized

Journal:

International Journal of Coronaviruses

Article:

Preconception Immunoglobulins and Complements as Potential Biomarkers in Unexplained Female Infertility in Saudi Arabia

Journal:

Fertility Biomarkers

Article:

Is Vagus Nerve Therapy a Potential Alzheimer's Disease Treatment?

Journal:

International Journal of Global Health

Article:

The Potential Usefulness of Peripheral Somatosensory Stimulation in Improving Sleep Quality in Patients with Insomnia

Journal:

Sleep And Sleep Disorder Research

Article:

Exploring the Endocannabinoid System: From Circadian Rhythms to Sleep Regulation and Potential Therapeutic Insights

Journal:

Sleep And Sleep Disorder Research

Article:

White Eared Kob (Kobuskobleucotis, Lichtenstein and Peters, 1854,) in Ethiopia; Migration Status, Potential Anthropogenic Threats and Conservation Directives from an Ecotourism Perspectives

Journal:

Wildlife

Article:

Potential of Energy Efficiency and Conservation Measures in Residential Buildings in Ghana (Case Study of Student Hostel)

Journal:

Energy Conservation

Article:

Sesame (Sesamum indicum L.) seeds and di ammonium phosphate (dap) potential for controlling Striga seed germination, sorghum growth and grain yield

Journal:

Precision Agriculture

Article:

Newborns' MicroRNA Expression as Potential Biomarkers for Disease Diagnosis

Journal:

International Journal of Neonatology