Substantia Nigra

Substantia nigra is a particularly important and well-studied area of the brain. This area is located in the midbrain and is involved in the regulation of movement through its communication with other areas of the brain. The substantia nigra contains neurons that produce a chemical called dopamine, which acts as a neurotransmitter in the brain. The loss of dopamine-producing neurons in the substantia nigra is a hallmark sign of Parkinson's disease. Parkinson's disease is a progressive neurodegenerative disorder that affects nearly 10 million people worldwide. Symptoms of Parkinson's disease include tremors, stiffness, slowed movement, and difficulties with balance and coordination. Researchers have been investigating the use of various therapies to not only manage the symptoms of Parkinson's disease but to also slow or halt the progression of the disease. One area of study that shows promise is the use of stem cells to replace the lost dopamine-producing neurons in the substantia nigra. This approach is still in the early stages of research and requires further investigation, but it holds great potential for future therapies. Overall, the substantia nigra and its involvement in the regulation of movement has been a subject of interest for many years. With ongoing research, we continue to gain a better understanding of this area of the brain and how it can be targeted for the development of new therapies for neurological disorders such as Parkinson's disease.


From: Neurobiology

Related Article For "Substantia Nigra"

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Article:

Concomitant in Vivo Voltammetric and Electrophysiological Analysis Indicate that Nociceptin/Orphanin FQ Affects Dopamine and then Serotonin Activities in Brain Substancia Nigra.

Journal:

International Physiology Journal