Research Topic · Peer-Reviewed

Prader-willi Syndrome

Prader-Willi Syndrome is a genetic disorder that occurs due to the absence or the loss of expression of certain genes on chromosome 15. This neurodevelopmental disorder affects various bodily functions such as growth, metabolism, muscle tone, and intellectual development. One of the significant manifestations of Pr…

Curated from this journal's research 📚 1 peer-reviewed article cited Cited 6× across the literature 🔖 ISSN 2470-5020 🗓 Reviewed June 2026

Overview

Prader-Willi Syndrome is a genetic disorder that occurs due to the absence or the loss of expression of certain genes on chromosome 15. This neurodevelopmental disorder affects various bodily functions such as growth, metabolism, muscle tone, and intellectual development. One of the significant manifestations of Prader-Willi Syndrome is insatiable hunger, which results in obesity and metabolic complications. This feature usually appears early in childhood, and without proper care and monitoring, may lead to life-threatening conditions such as diabetes and cardiovascular disease. Another consequence of Prader-Willi Syndrome is delayed intellectual development, which means children with the condition may have challenges with learning, speech, and communication. They may also have behavioral and emotional issues, such as autism spectrum disorder, obsessive-compulsive behaviors, and mood disorders. Early detection and management of Prader-Willi Syndrome are essential for improving the quality of life of affected individuals. Treatment includes a comprehensive approach that involves a team of healthcare professionals such as endocrinologists, dieticians, and therapists. The goal is to regulate food intake, improve muscle tone, manage behavioral issues, and develop cognitive and social skills. Research on Prader-Willi Syndrome is ongoing, with a focus on understanding the underlying genetic mechanisms and developing more effective treatment strategies. Ongoing studies aim to identify potential drug targets to alleviate symptoms such as hyperphagia and improve cognitive development. With advancements in scientific knowledge, neurological research and therapy to treat Prader-Willi Syndrome is improving the lives of those living with this condition.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

How this research is being cited

The 1 article above has been cited 6 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Prader-willi Syndrome, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Neurological Research and Therapy (ISSN 2470-5020).

Journal editorial board
ESRA DOGRU HUZMELI · Turkey Rajib Paul · India Ian J Martins · Australia

This page summarises published research for orientation; it is not medical or professional advice.