Oligodendroglioma is a type of brain cancer that affects the cells in the brain responsible for producing the protective coating (myelin) around nerve fibers. These cells are called oligodendrocytes, and their job is to provide insulation and support for nerve cells. Oligodendrogliomas are relatively rare, accounting for only 5-10% of all adult brain tumors. The symptoms of oligodendroglioma depend on the location and size of the tumor. Common symptoms include seizures, headaches, changes in personality or behavior, and weakness or numbness in the arms or legs. In some cases, there may be no symptoms at all until the tumor has grown large enough to cause compression or damage to surrounding tissues. Treatment for oligodendroglioma usually involves a combination of surgery, radiation therapy, and chemotherapy. The goal of surgery is to remove as much of the tumor as possible without causing lasting damage to the brain. Radiation therapy uses high-energy radiation to kill cancer cells, while chemotherapy uses drugs to target and destroy cancer cells throughout the body. Research into the causes, treatment, and prevention of oligodendroglioma is ongoing. Some studies have identified genetic mutations that may increase the risk of developing this type of brain tumor. Other studies are looking at new ways to target cancer cells with drugs or other therapies, while still others are investigating ways to improve the effectiveness of current treatments.

From: Neurobiology

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Editor-in-chief: Zheng Jiang, Department of Neuroscience, The Johns Hopkins University School of Medicine.
Publication Type: Open Access Journal
Description: The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood.