Research Topic · Peer-Reviewed

Mitochondria

Mitochondria are membrane-bound organelles found in nearly all eukaryotic cells that generate the majority of cellular adenosine triphosphate through oxidative phosphorylation along the electron transport chain located in the inner mitochondrial membrane. Beyond energy production, they regulate calcium homeostasis, …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 74× across the literature 🔖 ISSN 2470-5020 🗓 Reviewed July 2026

Overview

Mitochondria are membrane-bound organelles found in nearly all eukaryotic cells that generate the majority of cellular adenosine triphosphate through oxidative phosphorylation along the electron transport chain located in the inner mitochondrial membrane. Beyond energy production, they regulate calcium homeostasis, reactive oxygen species signaling, fatty-acid oxidation, biosynthetic pathways, and programmed cell death, and they carry their own genome inherited through the maternal line. Mitochondria are particularly abundant in metabolically demanding tissues, and neurons depend heavily on mitochondrial function for synaptic transmission, axonal transport, and maintenance of ion gradients. Mitochondrial dysfunction, including defects in oxidative phosphorylation, impaired quality control, and accumulation of oxidative damage, is implicated in primary mitochondrial diseases and in the pathophysiology of neurodegenerative and other disorders. Their study draws on bioenergetics, redox biology, and genetics, and examines how mitochondrial integrity is challenged by oxidative stress and how antioxidant defenses and metabolic regulators influence organelle function across tissues, from reproductive and hepatic cells to neurons. Understanding mitochondrial biology is central to elucidating energy metabolism, cellular aging, and the mechanisms by which bioenergetic failure contributes to disease, and remains an active focus of biomedical and neurological research.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

The antioxidant and hepatoprotective activities of two tea polysaccharides

Yu ZhiCorresponding author
College of Horticulture and Forestry Science, Huazhong Agricultural University, Key Laboratory of Horticultural Plant Biology, Ministry of Education, No. 1 Shizishan Street, Hongshan District, Wuhan City, Hubei Province, China 430070
Exact topic Antioxidant Activity Cited by 5 doi:10.14302/issn.2471-2140.jaa-17-1541

How this research is being cited

The 12 articles above have been cited 74 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Mitochondria, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Neurological Research and Therapy (ISSN 2470-5020).

Journal editorial board
Ian J Martins · Australia Giuseppe Lanza · Italy Ion Codreanu · United States

This page summarises published research for orientation; it is not medical or professional advice.