Epicardium is a term that refers to the outermost layer of the heart wall, which is made up of connective tissue covered by a layer of mesothelial cells. This layer is also known as the visceral pericardium and plays an essential role in the development of the heart during embryonic development. The heart wall consists of three layers, of which epicardium is the outermost layer. In recent years, epicardium has become an area of interest for neurological research and therapy. Scientists have discovered that epicardium-derived cells (EPDCs) have the potential to differentiate into neuronal cells, suggesting that epicardium may serve as a source for cellular therapy for neurological injuries. Furthermore, studies have shown that EPDCs can be harnessed to promote the regeneration of damaged nerve tissues, making them a promising candidate for the treatment of various neurological disorders, such as stroke or traumatic brain injuries. Researchers are now exploring how to harness the regenerative potential of these cells to promote the repair and regeneration of nerve tissues. In conclusion, epicardium is an essential source of cells for medical research, and research into its potential applications for neurological therapy is continually expanding. As scientists continue to uncover the amazing properties of these cells, it is clear that epicardium-derived therapies will play a significant role in shaping the future of neurological treatment and rehabilitation.

From: Neurobiology

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Editor-in-chief: Zheng Jiang, Department of Neuroscience, The Johns Hopkins University School of Medicine.
Publication Type: Open Access Journal
Description: The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood.