Research Topic · Peer-Reviewed

Atrophy

Atrophy is the wasting away, shrinkage, or decline in size and function of a cell, tissue, or organ, usually as a result of reduced cellular activity, loss of cells, or both. It can affect many parts of the body and arises from a range of causes, including disuse, loss of nerve supply, inadequate blood flow or nutri…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 40× across the literature 🔖 ISSN 2470-5020 🗓 Reviewed June 2026

Overview

Atrophy is the wasting away, shrinkage, or decline in size and function of a cell, tissue, or organ, usually as a result of reduced cellular activity, loss of cells, or both. It can affect many parts of the body and arises from a range of causes, including disuse, loss of nerve supply, inadequate blood flow or nutrition, hormonal changes, aging, and disease. In the nervous system, atrophy refers to the loss of neurons and their connections or the shrinkage of brain regions, a feature of many neurodegenerative conditions; medial temporal lobe atrophy, for example, is associated with mild cognitive impairment and Alzheimer's disease. In muscle, atrophy reduces fiber size and strength and can result from immobilization, aging, or disease. Because atrophy often reflects an underlying process, identifying and measuring it, frequently through imaging, helps in diagnosis, in tracking disease progression, and in evaluating therapies aimed at preserving or restoring tissue. Within the scope of Neurological Research and Therapy, which addresses disorders of the nervous system and their treatment, this page gathers peer-reviewed, open-access research relevant to atrophy and neurodegeneration, including work on brain atrophy in cognitive impairment and Alzheimer's disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 40 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Atrophy, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Neurological Research and Therapy (ISSN 2470-5020).

Journal editorial board
Ian J Martins · Australia Giuseppe Lanza · Italy Ion Codreanu · United States

This page summarises published research for orientation; it is not medical or professional advice.