Amyloid Plaques

Amyloid plaques are a pathological hallmark of many neurological disorders, including Alzheimer's disease. These plaques are formed by the accumulation of beta-amyloid fibrils in the brain, which can lead to neuronal death and cognitive impairment. Recent research in the field of neurological therapy has focused on finding ways to prevent or reduce the formation of amyloid plaques. One approach has been the use of antibodies to target and clear beta-amyloid from the brain. Another potential therapy is the use of small molecules that can disrupt the aggregation of beta-amyloid fibrils, preventing the formation of amyloid plaques. In addition to these targeted therapies, researchers are also exploring the role of lifestyle factors in preventing the formation of amyloid plaques. Exercise, healthy diet, and social engagement have all been shown to have a protective effect on the brain and may reduce the risk of neurological disorders associated with amyloid plaque formation. Finally, advances in imaging technology have allowed researchers to better understand the development and progression of amyloid plaques in the brain. This has led to earlier diagnoses and more effective treatments for patients with neurological disorders. Overall, the study of amyloid plaques and their role in neurological disorders is an important area of research, with significant implications for the development of new therapies and treatments.


From: Neurobiology

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Editor-in-chief: Zheng Jiang, Department of Neuroscience, The Johns Hopkins University School of Medicine.
Publication Type: Open Access Journal
Description: The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood.