Mitochondrial Diseases

Mitochondrial diseases are a group of genetic diseases that affect the mitochondria, which are the powerhouses of the cells. These diseases can be caused by mutations in either mitochondrial or nuclear DNA, and can cause a wide range of symptoms including neurodegeneration, muscle weakness, stroke-like episodes, seizures, and exercise intolerance. Treatment options for mitochondrial diseases are limited and can vary from diet and lifestyle modifications to medications, supplements, and other treatments. Research continues to explore the potential of gene therapy, stem cell transplantation, and shielding agents to treat these diseases. With an increasing understanding of the genetic and molecular basis of these diseases, treatments continue to be developed and improved to improve the quality of life of those affected.