Research Topic · Peer-Reviewed

Oncogene

An oncogene is a gene that, when mutated or abnormally expressed, has the potential to drive normal cells toward cancerous growth. Research published in Neoplasms examines oncogenes and related molecular mechanisms across multiple cancer types and contexts. Studies have investigated the role of specific genes in tum…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 18× across the literature 🔖 ISSN 2639-1716

Overview

An oncogene is a gene that, when mutated or abnormally expressed, has the potential to drive normal cells toward cancerous growth. Research published in Neoplasms examines oncogenes and related molecular mechanisms across multiple cancer types and contexts. Studies have investigated the role of specific genes in tumor formation, including CDC6, whose cytoplasmic retention has been shown to induce senescence in immortalized cells and suppress tumor development in mouse models. The journal has published work on somatic mutations in signal transduction pathways, such as interferon-gamma signaling molecules in uterine leiomyosarcoma and smoothened (SMO) mutations in melanoma. Additional research has explored transcriptional regulation through computational analysis of regulatory single nucleotide polymorphisms and transcription factor binding sites, as well as the molecular diagnosis of thyroid cancers, including medullary thyroid carcinoma. The journal has also examined oncogenic pathways in hairy cell leukemia and osteosarcoma in veterinary contexts. Understanding oncogenes and their regulatory networks is essential for elucidating cancer biology, identifying diagnostic markers, and developing targeted therapeutic strategies across diverse malignancies.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Genes in Tumor Formation

Isolde RiedeCorresponding author
Exact topic Journal of Hematology and Oncology Research Cited by 2 doi:10.14302/issn.2372-6601.jhor-19-2986

How this research is being cited

The 12 articles above have been cited 18 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.

A sample of recent works citing this journal's research on Oncogene, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Journal of Neoplasms (ISSN 2639-1716).

Journal editorial board
Argyrios Tzamalis · Greece Chi Leung CHIANG · Hong Kong Dajun Deng · China

This page summarises published research for orientation; it is not medical or professional advice.