Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth (CMT) Disease is a group of inherited neurological disorders that affects the peripheral nerves. This disorder is the most common inherited neurological disorder in the world, impacting an estimated one in 2,500 individuals. The symptoms of CMT can vary greatly among individuals, but typically include weakness and muscle atrophy in the lower legs, feet and hands, as well as sensory loss, foot deformities and sometimes balance problems. CMT can be caused by mutations in different genes, and is typically diagnosed through a combination of physical examination, family history and genetic testing. Treatment for CMT is focused on managing the symptoms and improving quality of life, and may include physical therapy, orthotics, mobility aids and medication.
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