Overview
KLH (Keyhole Limpet Hemocyanin) is a large molecule found in the blood of keyhole limpets, a species of mollusks. It has been widely used as an antigen for immunization research, due to its ability to elicit an immune response from a variety of hosts, including humans and other mammals. It has served as a model for the identification and characterization of antigenic determinants, and as a carrier for vaccine antigens. Furthermore, it has been used to study immunological tolerance, the development of specific immune responses, the regulation of antibody production, and the testing of vaccine effectiveness. KLH has also been used in histochemical staining of cell membranes, as well as in ELISA (Enzyme Linked Immunosorbent Assays) for detecting antibodies and antigens. Overall, KLH antigen is an important tool for research on immunity and immunological tolerance.