Overview
Hypotonic refers to a solution having a lower concentration of solutes compared to another solution, typically resulting in water movement across a semipermeable membrane from the hypotonic solution toward the more concentrated one. In biological contexts, hypotonic solutions cause cells to swell as water enters by osmosis. Research published in International Physiology Journal has examined hypotonic conditions in specific applied and basic science contexts. One study investigated practical immunization delivery in an urban hospital setting in India, where understanding solution tonicity is relevant to vaccine preparation and administration protocols. Another investigation focused on the chromosomes of Dictyostelium giganteum, a social amoeba, where hypotonic treatment is a standard cytogenetic technique used to swell cells and spread chromosomes for microscopic analysis and karyotyping. These studies reflect the breadth of hypotonic solution applications, from clinical practice where proper solution preparation affects patient safety and treatment efficacy, to laboratory research where controlled hypotonic exposure enables fundamental discoveries about cellular and genetic organization across diverse organisms.
Research published in this journal
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Chromosomes of Dictyostelium Giganteum
How this research is being cited
The 2 articles above have been cited 10 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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RajeevZachariah Kompithra et al. · 2025 · Indian Journal of Medical Microbiology
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V. Ramasubramanian et al. · 2025 · Journal of Association of Physicians of India
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2025 · Journal of the Association of Physicians of India
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Therdpong Thongseiratch et al. · 2024 · Vaccines
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2024 · Vaccines
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2023 · Healthline
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2023 · Healthline
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A. J. Penugonda et al. · 2022 · Journal of Family Medicine and Primary Care
A sample of recent works citing this journal's research on Hypotonic, linking to each citing work.