Hepatocytes are the principal functional cells of the liver, making up the large majority of its mass. They carry out the organ's central metabolic work, including the metabolism of carbohydrates, lipids, and proteins, regulation of blood glucose, synthesis of plasma proteins such as albumin and clotting factors, st…
Hepatocytes are the principal functional cells of the liver, making up the large majority of its mass. They carry out the organ's central metabolic work, including the metabolism of carbohydrates, lipids, and proteins, regulation of blood glucose, synthesis of plasma proteins such as albumin and clotting factors, storage of vitamins and glycogen, production of bile to aid digestion, and the detoxification and biotransformation of drugs, toxins, and metabolic waste. Arranged in plates around the liver's blood sinusoids, hepatocytes are highly active and regenerative, but they are also vulnerable to injury from toxins, oxidative stress, drugs, infection, and metabolic disease, and their damage underlies conditions ranging from hepatitis to cirrhosis. Research across the publisher's portfolio examines hepatocyte biology and liver injury directly, including studies of antioxidant and membrane properties in hepatocytes, structural changes in liver tissue induced by zinc oxide nanoparticles, and the protective effects of compounds such as quercetin against chemically induced hepatotoxicity. Such work probes how hepatocytes respond to stress and how their function can be protected. This page gathers peer-reviewed, open-access research relevant to hepatocytes, liver cell function, and the mechanisms of hepatic injury and protection.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 164 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.
A sample of recent works citing this journal's research on Hepatocytes, linking to each citing work.