Structural Biology in Drug Discovery

Structural biology is an essential field of research in drug discovery and development. It involves the study of the three-dimensional structure of proteins, nucleic acids, and other biological molecules, as well as their interactions with each other. This helps scientists understand how molecules are assembled and how they interact with each other or with drugs, which can provide invaluable insights into the underlying causes of diseases and pave the way for the development of novel drug treatments. Structural biology is also used to make predictive models of molecules, which can be used to structure modifications that could improve the effectiveness of drugs. This can lead to the development of more effective and efficient patient treatments.

← International Journal of Structural Biology

Related Articles

45 article(s) found

Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients

Full-text HTML Download PDF Download XML

Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients

Full-text HTML Download PDF Download XML

Evaluation of SterculiaUrens Gum as Novel Carrier for Oral Colon Targeted Drug Delivery System

Full-text HTML Download PDF Download XML

Discovery and Quantification in Mass Spectrometry-Based Proteomics

Full-text HTML Download PDF Download XML

Current Status of Nonsteroidal Anti-Inflammatory Drugs in Colorectal Cancer Prevention

Full-text HTML Download PDF Download XML

Preliminary Survey on The Termite Mounds, Their Interior Geometrics and The Termite Prevention from Infrastructural Construction at New Site of Ndola International Airport in Zambia

Full-text HTML Download PDF Download XML

Synthesis and Assessment of a New Tetrahydrogeraniol Derivative as Penetration Enhancer for Transdermal Drug Delivery

Full-text HTML Download PDF Download XML

A Successful Vancomycin Treatment of Multidrug-Resistant MRSA-Associated Canine Pyoderma

Full-text HTML Download PDF Download XML

Trends and inducing factors for illicit drug use in Grenada: Epoch 2001 – 2009.

Full-text HTML Download PDF Download XML

Functional, Structural and Contextual Analysis of a Variant of Uncertain Clinical Significance in BRCA1: c.5434C->G (p. Pro1812Ala)

Full-text HTML Download PDF Download XML

Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug

Full-text HTML Download PDF Download XML

Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy

Full-text HTML Download PDF Download XML

Profile of Similarity of Electron Withdrawing Structure Towards Analgesic-Anti-Inflammatory Activity of The Novel Isatin Analogue: Design and Implementation of Phase I Drug Discovery

Full-text HTML Download PDF Download XML

Sulfonamides: Historical Discovery Development (Structure-Activity Relationship Notes)

Full-text HTML Download PDF Download XML

Evaluation of Bacterial Population in the Saliva of Drug Addicts

Full-text HTML Download PDF Download XML

Quantitative Microbiological Risk Assessment: Underrated Tool in Process Improvement in Food Microbiology

Full-text HTML Download PDF Download XML

Drug Design Progress of In silico, In vitro and In vivo Researches

Full-text HTML Download PDF Download XML

Drug Abuse among Street Children

Full-text HTML Download PDF Download XML

The Pineal Hypothesis for Drug Dependence

Full-text HTML Download PDF Download XML

Why New Drugs, Treatments, and Medical Devices Still Needs to be Tested Clinically Before Making it Available in the Market?

Full-text HTML Download PDF Download XML

Successful Cascade of Care and Cure HCV in 5382 Drugs Users: How Increase HCV Treatment by Outreach Care, Since Screening to Treatment

Full-text HTML Download PDF Download XML

Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.

Full-text HTML Download PDF Download XML

Structural Equation Modeling to Detect Predictors of CD4 Cell Count Change due to Long Term Antiretroviral Therapy Administered to HIV-Positive Adults at Felege Hiwot Teaching and Specialized Hospital, Bahir Dar, Ethiopia

Full-text HTML Download PDF Download XML

Lipid Assemblies as Tools for Drug Delivery

Full-text HTML Download PDF Download XML

Assessment of Self Medication Practice and Drugs Storage Among South Sudanese Community in Addis Ababa, Ethiopia

Full-text HTML Download PDF Download XML

Assessment of Body Size by Structural Equation Model Using Anthropometric Traits of Fishermen Community: A Methodological Approach

Full-text HTML Download PDF Download XML

Structural Characterization and Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated Ofloxacin

Full-text HTML Download PDF Download XML

The Biology of Fall Army Worm (Spodopterafrugiperda. J. E. Smith) in Sudan

Full-text HTML Download PDF Download XML

Six Fractal Codes of Biological Life Unifying ATOMS, WAVES and INFORMATION: Perspectives in Exobiology, Cancers Basic Research and Artificial Intelligence Biomimetism Decisions Making

Full-text HTML Download PDF Download XML

Computational Systemic Biology for Toxicity Studies: A Mini Review of Previously Published Articles

Full-text HTML Download PDF Download XML

A Review on Drug Design by the Application of Computer

Full-text HTML Download PDF Download XML

Risk Management: Emerging critical issues during the hospital administration of drug therapy

Full-text HTML Download PDF Download XML

CalliphoraRomantis: Discovery of A New Species in The Field of Forensic Entomology

Full-text HTML Download PDF Download XML

Comprehensive Study of Structural, Optical and EPR Properties of Mn2+ Doped CdSe Nanocrystals

Full-text HTML Download PDF Download XML

A case of delayed allergy after cyanoacrylate closure of varicose veins, diagnosed by drug-induced lymphocyte stimulation test

Full-text HTML Download PDF Download XML

Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe

Full-text HTML Download PDF Download XML

Spirometric profile of people living with HIV on antiretroviral drugs in Abidjan

Full-text HTML Download PDF Download XML

The Application of Immunoglobulins Immune Response in the Discovery and Development of Safe Therapeutic Agents: A Review Article

Full-text HTML Download PDF Download XML

Measuring Quality Change in the Market for Anti-Ulcer Drugs

Full-text HTML Download PDF Download XML

The Heart Physiology in Fertile Female and The Heart Pathophysiology in Post Menopausal Female. The Contribution of Molecular Biology, Maintaining Cardiac Hemodinamy and Electrophysiology

Full-text HTML Download PDF Download XML

Exercises Pursued by Older Adults with Osteoarthritis and Their Structural Impacts are Hard to Uncover; a Scoping Review of Selected 1970-2024 Studies

Full-text HTML Download PDF Download XML

RBM45: Molecular, Cellular, and Evolutionary Biology

Full-text HTML Download PDF Download XML

Call to Action: The Need for Adverse Drug Event (ADE) Standardization and Codification Through Improved ADE Definitions, Documentation and Mapping, as well as More Refined Medication Definitions

Full-text HTML Download PDF Download XML

Toxicology and Drug Safety Issues: A Review Article

Full-text HTML Download PDF Download XML

Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy

Full-text HTML Download PDF Download XML