Sepsis is a life-threatening condition triggered by an infection. It occurs when the body's response to an infection causes inflammation and damage to body tissues and organs, eventually leading to organ failure. Sepsis is a leading cause of death in hospitals worldwide, and it is responsible for millions of deaths each year. Early recognition and treatment of sepsis is key to improving outcomes and saving lives. Treatment of sepsis typically includes antibiotics, as well as other supportive care, depending on the severity and progress of the disease. As early recognition is key, physicians and healthcare professionals should be aware of the signs and symptoms of sepsis, and should screen for sepsis in any patient with an infection. Timely diagnosis and treatment is critical for improving outcomes and returning the patient to health.