Voxel-based Morphometry

Voxel-based Morphometry (VBM) is a powerful imaging technique used in neuroimaging research to measure the differences in anatomy or function between different groups of individuals. VBM is based on the analysis of brain images collected by MRI (magnetic resonance imaging) or CT (computed tomography) scanners. It uses multi-dimensional analysis of the voxels (volumetric pixels) in the brain image to detect regional differences in the volume and structure of the brain. VBM can be used to investigate brain atrophy associated with neurodegenerative diseases, such as Parkinson’s and Alzheimer’s, as well as in neurodevelopmental disorders, such as autism, and in research into the effects of aging on the brain. Its use has proven useful for the study of neurological diseases and disorders in both clinical and research settings.