Wiskott-aldrich Syndrome
Wiskott-Aldrich Syndrome (WAS) is an inherited immunodeficiency disorder characterized by low levels of immunoglobulins and inadequate functioning of the protective pool of white blood cells. WAS affects males primarily, with a very small percentage of females who are carriers of the condition. Symptoms of WAS include recurrent bacterial and viral infections, skin problems, and abnormal bleeding. In severe cases, WAS can lead to life-threatening complications such as leukemia or an enlarged spleen. Treatment is focused on controlling and preventing infections and consists of antibiotics, immunoglobulin replacement, and bone marrow or stem cell transplants. With proper diagnosis and aggressive treatment, life expectancy has dramatically improved and many patients can live into adulthood. This progress in quality of life serves as a testament to the importance of early detection, adequate treatment, and close monitoring for those affected by WAS.
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