Mediators of Inflammation

Mediators of inflammation are a group of molecules that contribute to the development and maintenance of the inflammatory process. They are released by cells in response to injury, infection and/or other forms of irritants and are responsible for the various signs and symptoms seen in inflammation such as redness, swelling, pain and heat. These mediators play important roles in both the initiation and resolution of inflammation, making them essential in understanding the pathophysiology of inflammatory diseases and the development of therapies to treat them. Furthermore, the identification of these mediators has also proven to be important in the discovery of new biomarkers for diagnosis and prognosis of diseases.