Serine-threonine Kinases

Serine-threonine kinases are a large family of enzymes involved in many key biological processes. They act as signal transducers, transferring signals between a cell's environment and the interior of the cell and providing a mechanism for regulating cell growth and differentiation. By acting on various substrates, they have various roles in diverse signaling pathways in cell cycle regulation and signal transduction. They are essential to many cellular processes, including cell growth, differentiation, proliferation and apoptosis. They are important drug targets in many diseases, such as cancer and Alzheimer's disease, and are used in drug discovery and development.