Chemokines

Chemokines are a family of small, secreted proteins that play a major role in the recruitment of immune cells to sites of inflammation. They can act as chemoattractants, or attract immune cells toward sites of infection or tissue damage, or as chemo-repellents, pushing immune cells away from sites of inflammation. Chemokines are often secreted by cells in response to infection and tissue injury and are involved in a variety of biological processes, including leukocyte trafficking, cell adhesion, and inflammation. They are also important in the development and maintenance of the immune system, and in the progression of disease and pathological conditions. The ability to control chemokines has huge potential for medical treatments, including cancer therapy, autoimmune diseases, and HIV/AIDS.