Germline Mutation
Germline mutation is a genetic mutation that occurs during the formation of gametes or reproductive cells (sperm, eggs) and is passed from parent to child. It is a permanent change to the germline, passed on from generation to generation, and can be the cause of genetic diseases or abnormalities. It can also increase the risk of cancer in adults. Germline mutations have been studied to understand the genetic basis of diseases and to develop therapeutic strategies for their treatment. They have also been used in genetic screening for inherited diseases and for gene therapy.
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