Von Willebrand Disease
Von Willebrand Disease (VWD) is a type of inherited bleeding disorder caused by mutations in the von Willebrand factor gene. VWD affects the body's ability to form blood clots, resulting in excessive bleeding and bruising even after minor trauma. Symptoms may include nosebleeds, heavy or prolonged menstrual bleeding, and bleeding after dental procedures or surgery. VWD is the most common inherited bleeding disorder, affecting up to 1% of the population. Diagnosis is made through laboratory testing and requires lifelong treatment, which can include intravenous infusions of von Willebrand factor, clotting factor concentrates, and desmopressin. Early diagnosis and proper management of VWD can improve patient quality of life and help to prevent life-threatening complications.
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