Overview
Antibody specificity is the ability of an antibody to recognize and bind selectively to a particular antigen, distinguishing its target from the many other molecules present in the body. This selectivity comes from the antibody's variable regions, whose unique three-dimensional shape fits a specific molecular feature of the antigen called the epitope. Specificity is a defining property of the adaptive immune response, allowing antibodies to neutralize or mark for destruction particular viruses, bacteria, and other foreign substances while leaving the body's own tissues and unrelated molecules untouched. It also makes antibodies powerful tools in diagnostics and research, because their precise binding lets them detect and measure defined targets. In the context of antibiotic and infection-related research, antibody specificity is relevant to understanding immune defense against pathogens and to the assays used to identify and monitor them. Related work within the journal's scope includes studies employing immunoassay and immunogenomic approaches for monitoring infectious disease and cancer and an account of the development of the enzyme immunoassay and ELISA, methods whose reliability depends on specific antibody-antigen recognition. This page gathers peer-reviewed, open-access research relevant to antibody specificity and the immunological and diagnostic methods built on selective antigen binding.
Research published in this journal
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 7 articles above have been cited 16 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
2024 · International Journal of Molecular Sciences
-
Dewa Ayu et al. · 2024 · Warmadewa Minesterium Medical Journal
-
2024 · International Journal of Molecular Sciences
-
Vitor Rodrigues da Costa et al. · 2023 · Exploration of Immunology
-
2023 · Biosensors
-
2023 · Exploration of Immunology
-
2023 · Biosensors
-
CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons2022 · JCI Insight
A sample of recent works citing this journal's research on Antibody Specificity, linking to each citing work.